Our employees are able to develop their careers in exciting new medical technologies, and so can you.
Oxford Biomedica’s Process R&D team consists of experienced scientists and engineers that have extensive expertise in all aspects of upstream and downstream development. PR&D take processes from the laboratory “bench” scale and apply process expertise and engineering fundamentals for delivery to Manufacturing.
We are currently recruiting for a Scientist III, Upstream to join the team. The purpose of this role is to perform and report laboratory-based experiments or investigations in accordance with scientific or regulatory requirements in line with departmental objectives
Your responsibilities in this role would be:
Develop and optimize upstream processes for producing lentiviral vectors, working within the Process R&D group.
Design and execute small scale and laboratory scale bioreactor cell culture activities for scale-up/scale-down of existing bioprocesses. Support new product process development and scale-up activities. This requires working with miniature cell-cultivation systems and the scale-up to larger bioreactors.
Involvement in activities ranging from vector manufacture, process optimization, technology transfer, and process validation activities associated with the manufacture of new gene therapy vectors.
Perform routine cell culture activities.
Lead the design and execution of experiments /investigations in accordance with correct methodologies and procedures under the direction of the Team Leader or a senior scientist
Carry out such other tasks as are required from time to time for the efficient running of the Company’s business upon request from your line manager or a Director of the Company.
Analyse and interpret experimental data for reporting to stakeholders within OXB
Prepare written reports to a high standard and present data within the Process R&D group.
Liaise with other members of the Process R&D group and assist with other development activities where appropriate.
Liaise with diverse internal and external collaborators in order to streamline process activities, data interpretation and introduction of new technologies.
An understanding of, or experience in downstream processing would be beneficial.
Accountable for own performance in alignment with group objectives and deadlines.
Ensure a high standard of record keeping and documentation of experiments and investigations.
Contribute to the efficient and safe operation of the laboratory
Writing of departmental risk assessments, SOPs and other documentation where appropriate.
To be successful in this role, you will have the following skills and experience: