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Scientist IV, Vector Engineering

OXB-PRG-20-247
Competitive
Permanent
35 / per week - Full-Time
Cowley ,
Oxford

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

We are currently recruiting for a Scientist IV to join our Vector Engineering Group.  The purpose of this role is to plan, execute and report laboratory-based experiments or analytical investigations in accordance with scientific or regulatory requirements, in alignment with department objectives

Your responsibilities in this role would be:

  • To undertake laboratory projects within the Vector Innovation Team towards improved lentiviral vector design
  • Technically support broader projects within the Vector Innovation Team and wider Vector Engineering and Platform Research Groups as required
  • To be able to work independently and collaboratively according to the requirements of the project
  • To maintain knowledge in the field through scientific literature and conferences, and to report back items of interest accordingly
  • Accountable for own performance in alignment with group objectives and deadlines. Design and conduct experiments /investigations in accordance with correct methodologies and procedures under the direction of the Group Lead.
  • Ensure a high standard of record keeping and documentation of experiments and investigations in order that information is clearly captured and disseminated and reported.
  • Present scientific data at internal meetings and external venues such as conferences.
  • Will report to the Group Leader or his/her delegated grade 5 to 6 scientist.
  • Conduct research and technical support of the highest quality, largely in a single project area but will assist in other projects as the need arises.
  • Ensure correct training requirements are met and that the training record is kept correct and up to date
  • Ensure experimental data is submitted to PatentSafe in a timely manner.
  • May be responsible for maintenance of a laboratory area and/or important equipment.
  • Personally responsible for the completion of tasks in relation to their criticality.
  • Joint responsibility for maintenance and compliance of a GxP laboratory area and GxP “housekeeping” procedures.
  • Work will be conducted in accordance with the OXB quality management system.
  • Writing and reviewing of departmental documentation and SOP’s.
  • Preparation of reports and documents to support GxP and regulatory activities.

To be successful in this role, you will have the following skills and experience:

  • PhD or BSc/MSc Degree in an appropriate discipline with relevant post-qualification experience
  • Knowledge in Virology and gene therapy would be an advantage
  • Laboratory experience with particular emphasis on one or more of the following: Tissue Culture, qPCR, Molecular Biology, flow cytometry and handling virus/viral vectors
  • Demonstrate competency in performing laboratory tasks and general experimental procedures with expertise in protein purification.
  • Trained to operate equipment in accordance with OXB procedures and requirements. Responsibility for a single piece of equipment and the ability to troubleshoot.
  • Expertise in the use of complex instrumentation eg qPCR, FACS or using difficult biological procedures that requires a specialist knowledge or skill.
  • Understanding of laboratory health and safety requirements.
  • Sufficient understanding of the overall activities in the department to contribute useful ideas at meetings.
  • Familiar with the literature relating to project area.
  • Capable of interpreting results from experiments and drawing conclusions but may need guidance from senior scientists.
  • Capable of explaining clearly why an experiment is being conducted and how the experiments help the group meet their objectives.
  • Good knowledge of the overall research programme in your group.
  • Detailed knowledge of the Quality management reporting structure/responsibilities within OXB.
  • High regard for safety and display a high level of good laboratory citizenship.
  • Detailed knowledge of the regulatory requirements for analytical work (e.g. product specifications, stability testing guidelines etc) is required.

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