Your browser is unsupported!

Update your browser to view this website correctly

Firefox logo Chrome logo Safari logo Opera logo

Principal Scientist (Team Lead), Analytical, Process R&D

35 / per week - Full-Time
Cowley ,

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.

Our recent successes are driving significant growth. As such, we are looking to recruit a Principal Scientist (Team Lead, Analytcial to to lead a team of Scientists and Laboratory Technicians and effectively co-ordinate the daily activities to ensure PR&D timelines are met, whilst maintaining compliance with GLP/GMP & safety regulations, within Process R&D.

Specific Work Responsibilities and Deliverables

  • Responsible for the line management of a team of analytical scientists and laboratory technicians; including managing performance, motivating the team and carrying out recruitment activities.
  • Manage and prioritise the team’s workload and results, ensuring results are delivered on time and at appropriate levels of quality.
  • Perform assays, report results and QC check assays for release in accordance with local rules.
  • Review and approve training records, and where appropriate organize and conduct training.
  • Contribute to and/or lead trouble shooting and technical investigations.
  • Contribute to and/or lead both departmental and company initiatives/projects.
  • Write, review and approve PR&D Policies, SOPs, forms and technical reports.
  • Responsible for ensuring the GLP (and where necessary GMP) compliance of the laboratory and equipment.
  • Ensure all direct reports or persons involved in projects are fully trained and maintain a high standard of record keeping and documentation of experiments so that information is clearly captured, disseminated and reported.
  • Maintain awareness of upcoming technologies, and keep up to date with current literature and thinking.
  • Promote appropriate, effective communication within team, with members of other departments, and with external collaborators.
  • Contribute to cross departmental activities and provide expert advice and technical input where needed.
  • Maintain a safe working environment by ensuring appropriate H&S training, risk assessments and COSHH assessments are in place.

To succeed, you will have:


  • BSc, MSc or PhD (or equivalent) in a relevant Bioscience with an appropriate level of relevant laboratory experience.
  • Previous experience of working within an industrial analytical laboratory environment is beneficial
  • Laboratory technical experience in one or more of the following areas: cell culture, qPCR or ELISA.
  • Good understanding of lentiviral vectors (or other gene therapy vectors), and associated product quality attributes.
  • Line management experience.
  • A sound understanding of basic biopharmaceutical process development activities.
  • In-depth knowledge of the regulatory requirements for analytical work (e.g. product specifications, stability testing guidelines etc) is required.
  • Understanding of laboratory health and safety requirements to ensure reports and junior staff adhere to these.
  • Ability to work within GLP/GMP environment and maintain compliance.
  • Familiarisation with GMP work practices would be a benefit.

No agencies please



Benefits Summary

  • Competitive pension scheme     
  • Generous holiday entitlement
  • Private Health Care
  • Health Cashback Plan
  • Employee Assistance Plan (EAP)              
  • Life Assurance
  • Childcare Vouchers
  • Discount Portal
  • Discretionary Share Option Scheme
  • Discretionary Sharesave Scheme
  • Cycle To Work Scheme
  • Public Transport Season Ticket Loans

Powered by iintegra | Terms Of Service | Privacy Policy | Cookie Policy