Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.
Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.
Oxford Biomedica’s Design and Discovery Group (DDG) is expanding its therapeutic portfolio and looking to recruit an experienced scientist to support the development of our viral vectored-based gene therapy programmes. The Company has a platform of exclusive and pioneering technologies on which are designed, developed and manufactured unique gene- and cell-based medicines.
We are looking for a highly motivated and skilled scientist with particular expertise in viral vector gene therapies to work within our dynamic, research-orientated group. The successful candidates will be involved in:
Managing the delivery of gene therapy products for therapies currently under development.
Initiating and developing novel concepts and ideas in lentiviral-based gene therapy.
Producing and characterizing lentiviral vectors used in our therapeutic programmes.
Key skills and requirements:
PhD or equivalent in relevant bioscience (e.g. virology, molecular and/or cellular biology) and have several years’ post-doctoral experience in academia or industry demonstrated by a strong publication record.
Excellent lab-based skills with particular emphasis in cellular and molecular virology including but not limited to: viral vector production/purification, DNA/microbial cloning, RT-PCR, qPCR, immunoblotting/immunofluorescence, confocal microscopy, cell culture (adherent/suspension), protein characterisation, cell transfection and flow cytometry.
Demonstrated ability to manage and execute projects to aggressive timelines with capacity to adapt to rapid changes in project priorities.
Excellent written and verbal communication skills.
Excellent organisational and time management skills.
Good attention to detail.
Expertise in lentiviral vector gene therapies a distinct advantage.
Key responsibilities and accountabilities:
Lead/manage research in the disease pipeline.
Development and implementation of new pipelines in gene therapy.
Development and improvement of lentiviral vector technologies.
Independently manage daily research activities and support junior members of staff.
Keep excellent experimental/data records.
Support other members of the group and wider the Research Group as required.
Knowledge and experience of developing viral vector based therapies.
Industry experience in gene or cell therapies preferable.
A highly motivated, enthusiastic, positive attitude.
Demonstrated ability (by peer-reviewed publications) to work independently and with a good understanding of the field they are working within.
Ability to work well in a team setting and when appropriate, ensure others are able to perform the tasks to the benefit of the team’s objectives.
Demonstrated ability to generate and implement new ideas.