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35 / per week - Full-Time
Yarnton ,

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market.

This is an excellent opportunity to join the manufacturing department which has experienced significant growth and delivered tremendous results within the last 3 years.  You will be joining the team at the point where OXB stand to be the first commercial manufacturers of Lentiviral vector in the world, manufacturing the first licensed advanced therapy approved by the FDA.  Therefore we are looking for motivated people who want to make a difference, delivering advanced innovative treatments to patients with unmet needs.

Key responsibilities and accountabilities:

  • Largescale manufacture of ATMPs within GMP cleanroom facilities including:
    • Upstream adherent and/or suspension mammalian cell culture, transfection and harvest of viral vector products.
    • Downstream processing including clarification, chromatography, ultra/diafiltration and fill/finish activities.
  • Ensuring batch success by working using good aseptic techniques.
  • Preparing, cleaning and maintaining the GMP facility including performing viable and non-viable environmental monitoring.
  • Preparation of growth media and stock solutions using portable mixing tanks.
  • Completing Batch Manufacturing Records in a timely fashion throughout the manufacturing process.
  • Taking part in continuous improvement initiatives & development of production processes.
  • Investigating quality incidents, deviations and improving procedures.
  • Working to high standards of health & safety.

Key skills and requirements:

  • BSc Life Sciences or equivalent or experience of working within a biological or chemical GMP manufacturing environment.
  • Prior experience of working within an aseptic environment is advantageous but not essential.
  • Self-motivated with a strong focus on safety, quality, details and results.
  • Good problem solving, interpersonal communication and team skills.
  • Excellent writing skills and computer literacy.
  • Flexibility to work shifts (07:00 - 15:00 and 14:00 – 22:00) as dictated by the manufacturing schedule.

We look forward to receiving your application.

No agencies please.

Benefits Summary

  • Competitive pension scheme     
  • Generous holiday entitlement
  • Private Health Care
  • Health Cashback Plan
  • Employee Assistance Plan (EAP)              
  • Life Assurance
  • Childcare Vouchers
  • Discount Portal
  • Discretionary Share Option Scheme
  • Discretionary Sharesave Scheme
  • Cycle To Work Scheme
  • Public Transport Season Ticket Loans

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