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Vector Purification Research Scientist

35 / per week - Full-Time
Cowley ,

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market

Our recent successes are driving significant growth. As such, we are looking for a Vector Purification Research Scientist to join the Vector Engineering Group.  This team is involved in the design, development and production of lentiviral vectors for external and internal feasibility programs; the VPR team’s activities will be focused on the Downstream purification aspects of these activities.  This is a unique position within the industry to undertake pure research and transition new concepts into GMP compliant manufacturing arena.

The VPR team will have two over-arching aims: [1] transition early commercially relevant research-level technologies into the process research and development team, and [2] work closely with the Vector Service Team in generating vector preparations for collaborators and pre-clinical studies.

We are seeking a highly motivated individual to join the VPR team. The successful candidate will be involved in:

  • Testing new chromatography approaches in relation to lentiviral vector purification
  • Cross-group activities within Platform Research; transitioning novel technologies from concept/proof-of-principle into proven downstream purification paradigms
  • Vector preparations for collaborative studies
  • Early product feasibility studies for external clients

Key Tasks

  • Chromatography procedures e.g. ion-exchange, diafiltration, affinity purification
  • Analytics and sample management
  • Molecular biology techniques
  • Keep excellent experiment/data records
  • Support other members of both the VPR team and wider Research Department as required


Required Skills/Knowledge/Qualifications

  • Minimum of Masters or equivalent degree in a relevant Biological Science subject, or candidates with substantial experience in the Bioscience industry will be considered
  • Relevant chromatography experience including use of Akta and/or affinity purification of (ideally) viral vectors/vaccines
  • Demonstrable excellent lab-based skills
  • Demonstrable ability to work well in a team
  • Ability to demonstrate strong written and oral communication skills


  • Experience in downstream processing of viral vectors
  • Knowledge in basic virology/vectorology would be an advantage
  • Knowledge in upstream cell culture process development would be an advantage
  • Good intuition & problem solving skills

No agencies please

Discretionary Benefits available immediately:

  • Car Parking
  • On site catering (Windrush Court)
  • E-learning access
  • Professional subscription

Contractual benefits on completion of probation:

  • Generous pension
  • Private Medical Insurance
  • Group Life Assurance

Discretionary benefits on completion of probation:

  • Health Cashback Plan
  • Employee Assistance Plan
  • Childcare Vouchers
  • Discount Portal
  • Cycle To Work Scheme
  • Public Transport Season Ticket Loans

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