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Senior Scientist, CEG - 1 year maternity cover

OXB-CEG-18-172
Competitive
Contract
12 - Months
35 - 0 / per week - Full-Time
Cowley ,
Oxford

Oxford BioMedica is a pioneer of gene and cell therapy and our work is helping to deliver life changing treatments.

Gene and cell therapy is the treatment of disease by the delivery of therapeutic DNA into a patient’s cells, providing long term and potentially curative treatments for a wide range of diseases. With the potential to transform medicine, the sector holds significant promise with the first commercial products now launched and others rapidly approaching the market

Our recent successes are driving significant growth. As such, we are looking for a Senior Scientist in our Cell Engineering Group for a 1 year fixed term contract maternity cover

Profile of Role

Oxford BioMedica’s Cell Engineering Group (CEG) is part of the Platform Research Department. CEG is involved in the development of stable lentiviral vector packaging and producer cell lines. The CEG is recruiting a highly motivated Scientist with genome editing experience to assist with the engineering of stable lentiviral vector packaging and producer cell lines.

The successful candidates will be involved in:

  • Development of stable lentiviral vector packaging and producer cell lines using different genome-editing technologies.
  • Characterisation of resulting packaging and producer cell lines
  • An automated platform for the high throughput selection and screening of cell lines
  • The development and optimisation of lentiviral vector production
  • Other activities within the Platform Research Department

Key Tasks

  • Genome editing procedures e.g. CRISPR/Cas, ZNC, TALEN
  • Extensive cell culture
  • Molecular biology techniques
  • LV analytics
  • Organisation of parallel projects/activities
  • Support other members of both the CEG team and wider Platform Research Department as required

Required Skills/Knowledge/Qualifications

  • Post-doctoral/Industry experience in a relevant Biological Science subject
  • Expertise in genome editing technologies is essential 
  • Ability to work independently and as part of a hard-working, motivated and enthusiastic team
  • Extensive mammalian cell culture experience
  • Demonstrable excellent lab-based skills
  • Ability to supervise, train and motivate others
  • Ability to demonstrate strong written and oral communication skills

 Desirable

  • Experience with Next Generation Sequencing and bioinformatics would be an advantage
  • Experience working in a commercial/industry setting is preferred but not essential
  • Experience with line management is preferred but not essential
  • Knowledge in basic virology/vectorology would be an advantage
  • Experience with cell culture automation systems would be an advantage

Good intuition & problem solving skills

No agencies please


Benefits Summary

  • Competitive pension scheme     
  • Generous holiday entitlement
  • Private Health Care
  • Health Cashback Plan
  • Employee Assistance Plan (EAP)              
  • Life Assurance
  • Childcare Vouchers
  • Discount Portal
  • Discretionary Share Option Scheme
  • Discretionary Sharesave Scheme
  • Cycle To Work Scheme
  • Public Transport Season Ticket Loans

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